Why do oxycontin make you itchy

But they are highly addictive and have some unpleasant and potentially deadly side effects. Now a group of Scientists have discovered a Therapeutics that target the ScienceDaily shares links with sites in the TrendMD network and earns revenue from third-party advertisers, where indicated.

Print Email Share. Just a Game? Living Well. View all the latest top news in the environmental sciences, or browse the topics below:. Keyword: Search. When he blocked MOR1, the animals no longer received the drug's pain-killing benefits, but they continued to scratch.

It only transmits itch. Other side effects of opioids also have been extremely difficult to separate from the drugs' analgesic effects. But the current study makes Chen suspect that other variants of the receptor may be related to nausea, respiratory depression, constipation or other common side effects associated with the use of pain-killing drugs.

Chen hopes his research will motivate other investigators to look more closely at whether other opioid receptor variants may be responsible for these additional side effects. He says the finding opens up new possibilities for designing novel therapeutic strategies to relieve opioid-induced itching without blocking the analgesic effects of the drugs. Chen's team plans to look more closely at other opioid receptors to learn what they do, but he also hopes to quickly determine whether blocking MOR1D might alleviate itch people taking morphine or other opioids.

Materials provided by Washington University School of Medicine. Note: Content may be edited for style and length. Opioid-induced itching while suppressing pain sensation has been one of the mysteries for a long, long time. We found that this isoform is specifically required for relaying morphine-induced itch.

Very interestingly and unexpectedly, we found that this isoform is not involved in morphine analgesia. So this, actually, is the first evidence to show that a morphine isoform has nothing to do with morphine analgesia. Oxycodone belongs to the group of medicines called narcotic analgesics pain medicines. It acts on the central nervous system CNS to relieve pain. When oxycodone is used for a long time, it may become habit-forming, causing mental or physical dependence.

However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence addiction is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

This medicine is available only with your doctor's prescription. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals.

For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects of oxycodone and acetaminophen combination in the pediatric population.

Safety and efficacy have not been established. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of oxycodone and acetaminophen combination extended-release tablet, solution, or tablet in the elderly. However, elderly patients are more likely to have age-related kidney, heart, lung, or liver problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

Appropriate studies have not been performed on the relationship of age to the effects of oxycodone and acetaminophen combination capsules in the pediatric population. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.

In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.

Using alcohol or tobacco with certain medicines may also cause interactions to occur. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases.

If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. The presence of other medical problems may affect the use of this medicine.

Make sure you tell your doctor if you have any other medical problems, especially:.